Bone reconstruction

thttht
Posted:
in General Discussion edited January 2014
This is freaky, but cool:



New jaw bone grown in man?s back muscle

...

Warnke and his group began by creating a virtual jaw on a computer, after making a three-dimensional scan of the patient?s mouth.



The information was used to create a thin titanium micro-mesh cage. Several cow-derived pure bone mineral blocks the size of sugar lumps where then put inside the structure, along with a human growth factor that builds bone and a large squirt of blood extracted from the man?s bone marrow, which contains stem cells.



The surgeons then implanted the mesh cage and its contents into the muscle below the patient?s right shoulder blade. He was given no drugs, other than routine antibiotics to prevent infection from the surgery.



The implant was left in for seven weeks, when scans showed new bone formation. It was removed about eight weeks ago, along with some surrounding muscle and blood vessels, put in the man?s mouth and connected to the blood vessels in his neck.



Scans showed new bone continued to form after the transplant.




Wow!



The author really wanted to conflate stem cells into the story though. Still, the future is coming and it is both wonderful and frightening. When muscles, tendons, skin et al, are likewise replicated, oh my.

Comments

  • Reply 1 of 12
    wrong robotwrong robot Posts: 3,907member
    whoa.
  • Reply 2 of 12
    powerdocpowerdoc Posts: 8,123member
    Interesting. When I was working at the hospital I participate in this type of surgery : the Otorhinolaryngologist removed the cancerous tumor, and the plastic surgeon team make a composite (bone muscle skin) free flap from the hip or the fibula.

    It was an interesting procedure, but difficult long, and not totally safe.
  • Reply 3 of 12
    scottscott Posts: 7,431member
    I thought I saw a way you could use one of those 3D "printers" to do largely the same thing.
  • Reply 4 of 12
    powerdocpowerdoc Posts: 8,123member
    Quote:

    Originally posted by Scott

    I thought I saw a way you could use one of those 3D "printers" to do largely the same thing.



    It will be a good thing, but unfortunately artificial material in the mouth lead to infection.
  • Reply 5 of 12
    progmacprogmac Posts: 1,850member
    that damn socialist german health care system. no innovation at all.
  • Reply 6 of 12
    scottscott Posts: 7,431member
    Quote:

    Originally posted by Powerdoc

    It will be a good thing, but unfortunately artificial material in the mouth lead to infection.



    I think the bone grew into it and eventually consumed the material.
  • Reply 7 of 12
    powerdocpowerdoc Posts: 8,123member
    Titane is neutral for the bone. It allow a good osteo-integration. Others materials like silicon, glass, plastic erode bones at it's contact. That's why teeth implants are made of titane. Branemark from sweden did a great job of research in this aera some years ago. He is the father of modern teeth implants.
  • Reply 8 of 12
    scottscott Posts: 7,431member
    Maybe this is what I read about?



    http://www.itg.uiuc.edu/technology/reconstruction/
  • Reply 9 of 12
    powerdocpowerdoc Posts: 8,123member
    Quote:

    Originally posted by Scott

    Maybe this is what I read about?



    http://www.itg.uiuc.edu/technology/reconstruction/




    Thanks for the link, I understand better. Hydroxyapatite is a good material for bone reconstruction. With corail it allow osteointegration. I have use it, but in the form of small particles in the past with success.
  • Reply 10 of 12
    giaguaragiaguara Posts: 2,724member
    Interesting..



    A practical curiosity: how can he have slept all that time when the bone was growing in his back muscles? It must have felt like having a kidney crash ..
  • Reply 11 of 12
    powerdocpowerdoc Posts: 8,123member
    Quote:

    Originally posted by Giaguara

    Interesting..



    A practical curiosity: how can he have slept all that time when the bone was growing in his back muscles? It must have felt like having a kidney crash ..




    I guess it was unconfortable.
  • Reply 12 of 12
    giaguaragiaguara Posts: 2,724member
    No experience of growing bones in my back muscles .. but i guess, having a bit more material in the back could make it feel a bit nicer. it must be diffferent if you are 100 or 200 lbs.



    Of the other instead ... it was bad enough to keep me 2 weeks offline voluntarily. too sick to even touch a computer.
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