
No. HIV cannot spare to turn off things -- every mutation HIV conferring resistance to a drug has been on an actively used protein (and it doesn't matter that these organisms are turning off things anyway -- that means the things that aren't being used can be further modified, evolved to match some new needed function). Scientists are realizing this and trying to out design HIV's built in evolutionary device buy forcing new drugs to look as much like natural substrates as possible so that it would be all but impossible for HIV to mutate a resistance. But you know what, it might work a little better, but I suspect it will fail just the same. HIV is SOOOO smart.
Yes... you can and people have. Using a leaky polymerase people have done amazing things in the modification of protein function (there are other methods, of course, but the polymerase reactions are the most natural off them) selected, but not designed. In order to see anything on a laboratory time scale you have to increase the rate of mutation 10^6 to 10^9 times. This barely gets you over the preservation of function tendencies nature has evolved.
Why Behe thinks that e. coli or malaria is evolving any faster than than it has in the past, I will never know....
I also have to point out that MOST scientists aren't looking for spontaneous gain of function when they work with any of these organisms... I don't know of a single one looking at evolution at the scale of bacteria in any event...
Evolution is used as a theory to explain observed results... And like the young universal gravitation it has its yips that proclaim that it must be false because the moon hasn't crashed into the earth, and when the scientists respond that actually the moon is moving away from earth due to tidal effects, they proclaim that the end is nigh for gravitation...
Alright, that seems fair enough -- as long as Behe isn't pulling statistics out of thin air on the protein thing.
We are probably at a point of interpretation over whether we should be seeing bacteria, and viruses, things like malaria evolving new features. I'd imagine that's where the punditry will center.
In our desire to impose form on the world we have lost the capacity to see the form that is there;
and in that lies not liberation but alienation, the cutting off from things as they really are. --...
In our desire to impose form on the world we have lost the capacity to see the form that is there;
and in that lies not liberation but alienation, the cutting off from things as they really are. --...














