Best Self-Employment/Accounting SW?

in Mac Software edited March 2014
I'm looking for the best SW option for the Mac for being self-employed. IOW, using a 1099 series form and filing every 3 months.

PS: I'm also curious if there is an online calculator that will help find the levels of pay at which going to or from W2 and 1099 is more advantageous given hours works, location (i,e.: taxes), benefits, etc.
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