Unless it's an iPod from before the days of non windows/mac specific formating.
That said, I don't own an iPod, but my brother does and he plugs his windows formatted one into the Macs in the house all the time with no trouble. I don't know if it works the other way around though.
I have MacDrvie installed on a few PC's so that I can use my Mac formatted iPod on them. But it only allows you access to Mac formatted drives. It won't run Mac apps.
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Unless it's an iPod from before the days of non windows/mac specific formating.
That said, I don't own an iPod, but my brother does and he plugs his windows formatted one into the Macs in the house all the time with no trouble. I don't know if it works the other way around though.