Unfortunately, OmniWeb 4.x can't handle a lot of the dynamic HTML that iTools uses. So, either Apple hobbles iTools for those people who have more DHTML-capable browsers, or OmniGroup gets cracking on the 5.0 version of OW. Get which one is more likely to happen.
OmniWeb will work with most iTools functions, I've found, as long as it identifies itself as MSIE. Actually, there are a lot of sites out there, including several from MSN, that will give you the same trouble. As long as the browser tells the site that it's IE, most functions will work. For the MSN sites, though, you have to set it up as IE for Windows.
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There's a setting for this in preferences.