I've seen more problems with all-in-ones than I have with standalone components. My boss has one that continually has problems, and when one aspect of it is screwed-up, it tends to mess up the whole works. For example, if his toner is running low it doesn't want to let him receive a fax, which is reasonable, but it also doesn't want to let him scan to a file, or send a fax.
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Although I havent tried one, I rekon those big Mopiers would be awsome that the likes of HP sell!! But cost big $$$$