Marketcircle's Daylite, which I have previously dismissed for having a seriously outdated interface, has been upgraded to version 4.
It now has a much more modern look and a Sidebar-style interface.
Word on the Net seems to be that it was rushed to beat the June deadline for sandboxing, and as a result, users are reporting higher than normal bouts of crashing.
Oddly, Macworld hasn't done a single story on the new release. Since Daylite is the really the only Sales CRM game in town on the Mac platform, one would expect MacWorld to do a 'First Look' and then follow up with a complete review. This may speak to the idea that the release is known to be a bit shaky, and MW is waiting for a maintenance release before diving in.
FileMaker could be a solution. There are plenty free filemaker templates to use as a fundament.